Bisacodyl (INN) is a stimulant laxative drug that works directly on the colon to produce a bowel movement.

Acrylamide is a member of the class of acrylamides. It has a role as a carcinogenic agent a neurotoxin a mutagen an alkylating agent and a Maillard reaction product.

COH34 is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.